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Search Results for " orexin 2 receptor agonist "

10

Compounds

Cat No. Product Name Synonyms Targets
T3177 Orexin 2 Receptor Agonist OX2R OX Receptor
Orexin 2 Receptor Agonist (OX2R) is an effective (EC50: 23 nM) and OX2R-selective (OX1R/OX2R EC50 ratio: 70) agonist.
T39561 Orexin 2 Receptor Agonist 2
Orexin 2 Receptor Agonist 2 (ORA-2) is a specific agonist for the orexin 2 receptor.
T39229 YNT-185 OX Receptor
YNT-185 is a nonpeptide, selective agonist of the orexin type-2 receptor (OX2R), demonstrating EC50 values of 0.028 μM and 2.75 μM for OX2R and OX1R, respectively. Furthermore, YNT-185 effectively alleviates symptoms of ...
T39808 Firazorexton
Firazorexton is a potent orexin type 2 receptor (OX2R) agonist.
TP1975L [Ala11,D-Leu15]-Orexin B acetate [Ala11,D-Leu15]-Orexin B acetate (532932-99-3 Free base) OX Receptor
[Ala11,D-Leu15]-Orexin B acetate is a selective agonist of orexin-2 receptor (OX2) with an EC50 of 0.13 nM, showing 400-fold selectivity over OX1 (52 nM).
T75921 [Ala11,D-Leu15]-Orexin B(human) TFA
[Ala11,D-Leu15]-Orexin B(human) TFA is a potent, selective agonist for the orexin-2 receptor (OX2), demonstrating 400-fold higher selectivity for OX2 (EC 50 =0.13 nM) compared to the orexin-1 receptor (OX1) with an EC 50...
T75922 OXA(17-33) TFA
OXA(17-33) TFA is a potent, selective agonist for the orexin-1 receptor (OX1), demonstrating about 23-fold higher affinity for OX1 (EC50 = 8.29 nM) compared to the orexin-2 receptor (OX2) (187 nM) [1].
T75925 Orexin B, rat, mouse TFA
Orexin B, rat, mouse (Rat orexin B) TFA, an endogenous agonist for orexin receptors, binds to and activates the closely related orphan G protein-coupled receptors OX1-R and OX2-R. This compound is instrumental in stimula...
T37112 YNT-185 dihydrochloride
Potent and selective orexin OX2 receptor agonist (EC50 = 28 nM at human OX2 expressed in CHO cells). Displays approximately 100-fold selectivity for OX2 over OX1 (EC50 = 2.75 μM at human OX1 expressed in CHO cells). Depo...
T78636 Firazorexton hydrate TAK-994
Firazorexton hydrate (TAK-994) is a brain-penetrant and orally active agonist of the orexin type 2 receptor (OX2R) with a potent EC50 of 19 nM. It effectively reduces wakefulness fragmentation and cataplexy-like episodes...
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